The chemical properties of alicyclic heterocycles are similar to those of the corresponding chain compounds. Compound: 5-Bromo-3-methoxypyridin-2-amine, is researched, Molecular C6H7BrN2O, CAS is 42409-58-5, about Emergence of Highly Enantioselective Catalytic Activity in a Helical Polymer Mediated by Deracemization of Racemic Pendants, the main research direction is enantioselective catalytic helical polymer deracemization racemic pendant.Application of 42409-58-5.
Any polymers composed of racemic repeating units are obviously optically inactive and hence chiral functions, such as asym. catalysis, will not be expected at all. Contrary to such a preconceived notion, we report an unprecedented helical polymer-based highly enantioselective organocatalyst prepared by polymerization of a racemic monomer with no catalytic activity. Both the right- and left-handed helical poly(biarylylacetylene)s (PBAs) composed of dynamically racemic 2-arylpyridyl-N-oxide monomer units with N-oxide moieties located in the vicinity of the helical polymer backbone can be produced by noncovalent interaction with a chiral alc. through deracemization of the biaryl pendants. The macromol. helicity and the axial chirality induced in the PBAs are retained (“”memorized””) after complete removal of the chiral alc. Accordingly, the helical PBAs with dual static memory of the helicity and axial chirality show remarkable enantioselectivity (86% ee) for the asym. allylation of benzaldehyde. The enantioselectivity is slightly lower than that (96% ee) of the homochiral PBAs prepared from the corresponding enantiopure (R)- and (S)-monomers, but is comparable to that (88% ee) of the helical PBA composed of nonracemic monomers of ca. 60% ee.
There is still a lot of research devoted to this compound(SMILES：BrC1=CN=C(C(=C1)OC)N)Application of 42409-58-5, and with the development of science, more effects of this compound(42409-58-5) can be discovered.
Reference:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem