He, Zhen-Hong; Wei, Yuan-Yuan; Li, Na; Sun, Yong-Chang; Yang, Shao-Yan; Wang, Kuan; Wang, Weitao; Ma, Xiaoxue; Liu, Zhao-Tie published the artcile< N-formylation of isoquinoline derivatives with CO2 and H2 over a heterogeneous Ru/ZIF-8 catalyst>, Recommanded Product: 5-Methoxyisoquinoline, the main research area is isoquinoline derivative formylation heterogeneous calayst property.
Chem. utilization of CO2 is one of the fundamental strategies to synthesize value-added chems. and reduce the CO2 emission. N-formyl-1,2,3,4-tetrahydroisoquinoline derivatives (FTHIQs) are important chems. for the synthesis of medical intermediates and alkaloids. N-formylation of isoquinoline derivatives (IQs) with CO2 is an ideal protocol to synthesize the FTHIQs and utilize the CO2 source. In the present work, we prepared a heterogeneous Ru/ZIF-8 catalyst with a Ru loading of 2 wt% by a simple impregnation method and assessed its performances in the N-formylation of IQs and CO2 with H2. The Ru/ZIF-8 catalyst offered high IQ conversion of 98% and FTHIQ selectivity of 93% in the reaction under relatively mild conditions (150°C, 2 MPa CO2, and 6 MPa H2). The catalyst possessed good universality and reusability, showing a potential in wide application of N-formylation of highly unsaturated nitrogen-containing isoquinolines.
Journal of Experimental Nanoscience published new progress about Catalyst supports. 90806-58-9 belongs to class isoquinoline, and the molecular formula is C10H9NO, Recommanded Product: 5-Methoxyisoquinoline.
Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem