Patil, Bhausaheb N.’s team published research in Tetrahedron Letters in 2019-03-28 | CAS: 104-01-8

Tetrahedron Letters published new progress about Benzothiadiazines Role: SPN (Synthetic Preparation), PREP (Preparation). 104-01-8 belongs to class isoquinoline, name is 4-Methoxyphenylacetic acid, and the molecular formula is C9H10O3, Related Products of isoquinoline.

Patil, Bhausaheb N. published the artcileTransition metal-catalyzed C-H functionalization of arylacetic acids for the synthesis of benzothiadiazine 1,1-dioxides, Related Products of isoquinoline, the main research area is benzothiadiazine dioxide preparation; aminobenzenesulfonamide arylacetic acid functionalization condensation copper catalyst.

Copper-catalyzed practical route for the synthesis of benzothiadiazine 1,1-dioxides I [R = Ph, 4-FC6H4, 3-ClC6H4, etc.] and II [R1 = Ph, 2-furyl, 2-thienyl, etc.] was developed via C-H functionalization of arylacetic acids to form aromatic aldehydes and their subsequent condensation with 2-aminobenzenesulfonamide. This functional group tolerant approach furnished benzothiadiazine 1,1-dioxide derivatives in good to excellent yields. Broad substrate scope, inexpensive catalyst and high product yields were notable features of this protocol.

Tetrahedron Letters published new progress about Benzothiadiazines Role: SPN (Synthetic Preparation), PREP (Preparation). 104-01-8 belongs to class isoquinoline, name is 4-Methoxyphenylacetic acid, and the molecular formula is C9H10O3, Related Products of isoquinoline.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem