Mokrov, G. V. published the artcileSynthesis and Cardiotropic Activity of Linear Methoxyphenyltriazaalkanes, Name: 2,3-Dimethoxybenzaldehyde, the main research area is methoxyphenyltriazaalkane preparation antiischemic antiarrhythmic antifibrillatory cardiotropic activity.
A new group of potential pFOX inhibitors among linear methoxyphenyltriazaalkanes RCH2NH(CH2)nNH(CH2)mNHCH2R (R = 2,3-(OCH3)2C6H3, 2,4-(OCH3)2C6H3, 2,5-(OCH3)2C6H3, 2,3,4-(OCH3)3C6H2, 2,4,5-(OCH3)3C6H2, 2,4,6-(OCH3)3C6H2; n = 2, 3; m = 2, 3) were designed and synthesized. Cardiotropic activity in rodent experiments was found for most of the synthesized compounds The most active compound RCH2NH(CH2)nNH(CH2)mNHCH2R (R = 2,3,4-(OCH3)3C6H2; n = 2; m = 2) combined with anti-ischemic, antiarrhythmic, and antifibrillatory activities (1 mg/kg, i.v.) and low toxicity (LD50 = 119 mg/kg, mice, i.p.) was selected for development as a potential cardiotropic drug.
Pharmaceutical Chemistry Journal published new progress about Amines Role: PAC (Pharmacological Activity), SPN (Synthetic Preparation), THU (Therapeutic Use), BIOL (Biological Study), PREP (Preparation), USES (Uses). 86-51-1 belongs to class isoquinoline, name is 2,3-Dimethoxybenzaldehyde, and the molecular formula is C9H10O3, Name: 2,3-Dimethoxybenzaldehyde.
Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem