Peczkowski, Gary R. published the artcile2,7-Diazabicyclo[2.2.1]heptanes: novel asymmetric access and controlled bridge-opening, Safety of 4-Methoxyphenylacetic acid, the main research area is diazabicycloheptane preparation; oxoalkyl triketopiperazine enantioselective preparation rearrangement; triketopiperazine enone Michael addition organocatalyst.
An efficient method was developed for the asym. synthesis of oxoalkyl triketopiperazines I [R = H, Me, Et, Ph; Ar = Ph, 4-BrC6H4, 2-furanyl, etc.] via organocatalyzed Michael addition of triketopiperazines to enones in high yields and enantiomeric ratio. These triketopiperazines I underwent rearrangement to afford 2,7-diazabicyclo[2.2.1]heptanes II and further modification delivered products possessing natural product scaffolds including prolinamide and harmicine.
Chemical Communications (Cambridge, United Kingdom) published new progress about Enantioselective synthesis. 104-01-8 belongs to class isoquinoline, name is 4-Methoxyphenylacetic acid, and the molecular formula is C9H10O3, Safety of 4-Methoxyphenylacetic acid.
Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem