Tomar, Radha published the artcileExpanding the Utility of Inexpensive Pyridine-N-oxide Directing Group for the Site-selective sp2/sp3γ-C-H and sp2δ-C-H Functionalization of Carboxamides, Quality Control of 104-01-8, the main research area is pyridine oxide based biarylacetamide preparation regioselective; heteroaryl based biaryl carboxamide preparation regioselective; tricyclic quinolone preparation regioselective; arylheteroarylmethane preparation regioselective.
In this paper, the scope of pyridine-N-oxide DG was examined for accomplishing the site-selective (mono) γ-C(sp2)-H arylation in substrates containing competitive C(sp3)-H and C(sp2)-H bonds. The investigation had enabled to assemble a library of pyridine-N-oxide-based biarylacetamides, heteroaryl-based biaryl carboxamides, tricyclic quinolones, arylheteroarylmethanes, biaryl-based aliphatic carboxamides and mono (ortho) arylated phenylglycine derivatives In general, biaryl derivatives and in particular, arylacetamide, arylacetic acid derivatives and pyridine-N-oxide (2-aminopyridyl) motifs were medicinally relevant classes of compounds This work enabled the assembling of a library of the above-mentioned types of compounds through the pyridine-N-oxide directing group-aided site-selective sp2/sp3γ-C-H and sp2δ-C-H functionalization of carboxamides.
Asian Journal of Organic Chemistry published new progress about Arylation. 104-01-8 belongs to class isoquinoline, name is 4-Methoxyphenylacetic acid, and the molecular formula is C9H10O3, Quality Control of 104-01-8.
Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem