Lam, Raphael H. published the artcileSelective formylation or methylation of amines using carbon dioxide catalyzed by a rhodium perimidine-based NHC complex, Recommanded Product: 4-Methoxy-N-methylaniline, the main research area is rhodium perimidine NHC complex formylation methylation catalyst.
Carbon dioxide can play a vital role as a sustainable feedstock for chem. synthesis. To be viable, the employed protocol should be as mild as possible. Herein we report a methodol. to incorporate CO2 into primary, secondary, aromatic or alkyl amines catalyzed by a Rh(I) complex bearing a perimidine-based NHC/phosphine pincer ligand. The periminide-based ligand belongs to a class of 6-membered NHC ligand accessed through chelate-assisted double C-H activation. N-Formylation and -methylation of amines were performed using a balloon of CO2, and phenylsilane as the reducing agent. Product selectivity between formylated and methylated products was tuned by changing the solvent, reaction temperature and the quantity of phenylsilane used. Medium to excellent conversions, as well as tolerance to a range of functional groups, were achieved. Stoichiometric reactions with reactants employed in catalysis and time course studies suggested that formylation and methylation reactions of interest begin with hydrosilylation of CO2 followed by reaction with amine substrates.
Green Chemistry published new progress about Amines Role: SPN (Synthetic Preparation), PREP (Preparation). 5961-59-1 belongs to class isoquinoline, name is 4-Methoxy-N-methylaniline, and the molecular formula is C8H11NO, Recommanded Product: 4-Methoxy-N-methylaniline.
Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem