Ma, Chang published the artcile(4 + 2) Annulation of Cl-NH3+CH2SiMe2CH2Cl and Propynones for the Synthesis of 1,3-Azasilinones, Application of 2-Methyl-3-(3,4-methylenedioxyphenyl)propionaldehyde, the main research area is chloromethyl silyl methylammonium chloride reagent preparation annulation propynone; azasilinone preparation reactivity; silaazacycle bioactive mol preparation.
A useful 1,3-N,Si reagent (Cl-NH3+CH2SiMe2CH2Cl) and its (4 + 2) annulation with propynones were developed. The (4 + 2) annulation is promoted by NaHCO3via an intermol. N-1,4-addition/intramol. alkylation process, leading to 1,3-azasilinones in good yields. Diverse functionalization of the alkene, carbonyl, and N moieties on the 1,3-azasilinone was demonstrated, showcasing the potential of the approach in the synthesis of bioactive mols. containing silaazacycles.
Organic Letters published new progress about Aldehydes Role: RCT (Reactant), RACT (Reactant or Reagent). 1205-17-0 belongs to class isoquinoline, name is 2-Methyl-3-(3,4-methylenedioxyphenyl)propionaldehyde, and the molecular formula is C11H12O3, Application of 2-Methyl-3-(3,4-methylenedioxyphenyl)propionaldehyde.
Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem