Yang, Jie published the artcileSynthesis and biological evaluation of 3-arylcoumarins as potential anti-Alzheimer’s disease agents, Safety of 4-Methoxyphenylacetic acid, the main research area is synthesis arylcoumarin Alzheimer disease agent; 3-Arylcoumarin; Alzheimer’s disease; antioxidant activity; cholinesterase inhibitors; monoamine oxidase inhibitors.
Alzheimer’s disease, a neurodegenerative illness, has the extremely complex pathogenesis. Accumulating evidence indicates there is a close relationship between several enzymes and Alzheimer’s disease. Various substituted 3-arylcoumarin derivatives were synthesized, and their in vitro activity, including cholinesterase inhibitory activity, monoamine oxidase inhibitory activity, and antioxidant activity were investigated. Most of the compounds exhibited high activity; therefore 3-arylcoumarin compounds have the potential as drug candidates for the treatment of Alzheimer’s disease.
Journal of Enzyme Inhibition and Medicinal Chemistry published new progress about Alzheimer disease. 104-01-8 belongs to class isoquinoline, name is 4-Methoxyphenylacetic acid, and the molecular formula is C9H10O3, Safety of 4-Methoxyphenylacetic acid.
Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem