84468-15-5, Isoquinoline-5-sulfonyl chloride is a isoquinoline compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
EXAMPLE 5 In 50 ml of a chloroform solution containing 1.4 g of 3-dimethylaminopropylamine and 1.4 g of triethylamine was added dropwise 30 ml of a chloroform solution containing 2.6 g of 5-isoquinolinesulfonyl chloride under cooling with ice. After the dropwise addition of the chloroform solution, the mixed solution was stirred at a temperature of 2 C. to 10 C. for four hours, and the reaction mixture solution was washed with water and dried with anhydrous magnesium sulfate. After the chloroform was distilled therefrom, the residue obtained was subjected to a silica gel column chromatography (silica gel: 70 g; solvent: chloroform) to give 2.38 g of N-(3-dimethylaminopropyl)-5-isoquinolinesulfonamide, i.e., Compound (17) in a yield of 71%. Mass spectrum (m/e): 293, 249, 235, 221 and 207 NMR spectrum (CDCl3): 1.6(2H, CH2), 2.0-2.6(8H, 2*NCH3 +NCH2), 3.1(2H, NCH2), 6.2(NH), 7.4-7.7(1H), 8.0-8.6(4H) and 9.3(1H) IR absorption spectrum (numaxcap, cm-1): 2950, 2860, 2840, 1460, 1320, 1150, 1130, 830 and 760., 84468-15-5
84468-15-5 Isoquinoline-5-sulfonyl chloride 3371655, aisoquinoline compound, is more and more widely used in various fields.
Reference£º
Patent; Asahi Kasei Kogyo Kabushiki Kaisha; Hidaka; Hiroyoshi; US4456757; (1984); A;,
Isoquinoline – Wikipedia
Isoquinoline | C9H7N – PubChem