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Here is a brief introduction to this compound(13599-22-9)Reference of 1,5-Diphenyl-1H-pyrazole-3-carboxylic acid, if you want to know about other compounds related to this compound(13599-22-9), you can read my other articles.

Most of the compounds have physiologically active properties, and their biological properties are often attributed to the heteroatoms contained in their molecules, and most of these heteroatoms also appear in cyclic structures. A Journal, Article, ACS Medicinal Chemistry Letters called Design and Evaluation of Bispidine-Based SARS-CoV-2 Main Protease Inhibitors, Author is Shcherbakov, Dmitriy; Baev, Dmitriy; Kalinin, Mikhail; Dalinger, Alexander; Chirkova, Varvara; Belenkaya, Svetlana; Khvostov, Aleksei; Krut’ko, Dmitry; Medved’ko, Aleksei; Volosnikova, Ekaterina; Sharlaeva, Elena; Shanshin, Daniil; Tolstikova, Tatyana; Yarovaya, Olga; Maksyutov, Rinat; Salakhutdinov, Nariman; Vatsadze, Sergey, which mentions a compound: 13599-22-9, SMILESS is OC(=O)C1=NN(C(=C1)C1=CC=CC=C1)C1=CC=CC=C1, Molecular C16H12N2O2, Reference of 1,5-Diphenyl-1H-pyrazole-3-carboxylic acid.

For the first time, derivatives of 3,7-diazabicyclo[3.3.1]nonane (bispidine) were proposed as potential inhibitors of the SARS-CoV-2 main viral protease (3-chymotrypsin-like, 3CLpro). Based on the created pharmacophore model of the active site of the protease, a group of compounds were modeled and tested for activity against 3CLpro. The 3CLpro activity was measured using the fluorogenic substrate Dabcyl-VNSTLQSGLRK(FAM)MA; the efficiency of the proposed approach was confirmed by comparison with literature data for ebselen and disulfiram. The results of the experiments performed with bispidine compounds showed that 14 compounds exhibited activity in the concentration range 1-10μM, and 3 samples exhibited submicromolar activity. The structure-activity relationship studies showed that the mols. containing a carbonyl group in the ninth position of the bicycle exhibited the maximum activity. Based on the exptl. and theor. results obtained, further directions for the development of this topic were proposed.

Here is a brief introduction to this compound(13599-22-9)Reference of 1,5-Diphenyl-1H-pyrazole-3-carboxylic acid, if you want to know about other compounds related to this compound(13599-22-9), you can read my other articles.

Reference:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem