Quality Control of 2-(4-(tert-Butoxycarbonyl)piperazin-1-yl)acetic acid. Aromatic compounds can be divided into two categories: single heterocycles and fused heterocycles. Compound: 2-(4-(tert-Butoxycarbonyl)piperazin-1-yl)acetic acid, is researched, Molecular C11H20N2O4, CAS is 156478-71-6, about A combinatorial approach to new DNA minor groove binders. Author is Behrens, Carsten; Nielsen, Peter E..
A combinatorial approach towards new DNA minor groove binders capable of recognizing GC base pairs is reported. From a partly AT-biased library of 5832 different octapeptides of the type Py-Py-X1-X2-X3-Py-Py-γAbu synthesized following the one bead one compound methodol., two compounds containing the central peptide sequences Val-βAla-Tyr and Pip-βAla-Tyr were selected by a fluorescence-double stranded DNA probing assay using the sequence 5′-TTTGTTT-3′ as the probe. The two hits were independently synthesized and binding to a recombinant pUC-19 EcoRl/Pvull DNA restriction fragment containing the sequence 5′-TTTGTTT-3′ demonstrated. Binding constants to eight targets in the DNA fragment were estimated from quant. DNAse I footprinting.
There is still a lot of research devoted to this compound(SMILES：O=C(O)CN1CCN(C(OC(C)(C)C)=O)CC1)Quality Control of 2-(4-(tert-Butoxycarbonyl)piperazin-1-yl)acetic acid, and with the development of science, more effects of this compound(156478-71-6) can be discovered.
Reference:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem