Ding, Siyi published the artcileSilver(I)-mediated oxidation/cyclization of acrylamides with alkyl trifluoroborates, Formula: C8H11NO, the main research area is oxindole preparation silver mediated; acrylamide alkyl trifluoroborate tandem oxidative cyclization.
A mild silver-mediated oxidative cyclization of acrylamides I (R1 = H, 4-MeO, 4-Cl, 2-F; R2 = Me, i-Pr) has been developed by using alkyl trifluoroborates R3BF3K (R3 = i-Bu, EtCOCH2CH2, MeO2CCHMeCH2, cyclopentyl, PhCH2CH2, etc.) as radical precursors. It proceeds through a tandem radical addition/cyclization process, in which two new carbon-carbon bonds were formed. This protocol allows reliable and practical access to build the skeleton of 3,3-disubstituted oxindoles II in moderate yields; the readily available starting reagents, broad substrate scope and mild reaction conditions are the characteristic features of this protocol.
Synthetic Communications published new progress about Fluoroborates Role: RCT (Reactant), RACT (Reactant or Reagent) (alkyl). 5961-59-1 belongs to class isoquinoline, name is 4-Methoxy-N-methylaniline, and the molecular formula is C8H11NO, Formula: C8H11NO.
Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem