Semleit, Nina published the artcileControlling the Gold(I)-Catalyzed 1,5-Allenene Reaction: Construction of Fused Rings with Excellent Diastereoselectivity, HPLC of Formula: 151-10-0, the main research area is fused tricyclic compound preparation diastereoselective; allenene oxygen carbon nucleophile exo cyclization gold catalyst.
In the present study, the gold(I)-catalyzed reaction of 1,5-allenenes was controlled in such a way that instead of a [2+3] cycloaddition, a 5-exo-cyclization with the formation of a carbocation occurred. The latter could be trapped with both oxygen and carbon nucleophiles. In the investigated system, fused tricyclic frameworks I (R = Me; R1 = Me, Cl, Br, etc.; Nu = OMe, OEt, 2-furyl, etc.) with three contiguous stereocenters with excellent chemo- and diastereoselectivity in up to 95% yield were obtained.
Organic Letters published new progress about Chemoselectivity. 151-10-0 belongs to class isoquinoline, name is 1,3-Dimethoxybenzene, and the molecular formula is C8H10O2, HPLC of Formula: 151-10-0.
Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem