Guo, Hai-Ming published the artcileL-Prolinamide-catalyzed direct nitroso aldol reactions of α-branched aldehydes: a distinct regioselectivity from that with L-proline, Category: isoquinoline, the main research area is direct enantioselective nitroso aldol reaction aldehyde nitrosobenzene prolinamide catalyst.
The first direct enantioselective N-nitroso aldol reaction of aldehydes with nitrosobenzene catalyzed by an L-prolinamide derivative is presented; the reactions proceed smoothly furnishing the α-hydroxyamino carbonyl compounds, the otherwise disfavored products, in good yields with up to 64% ee. E.g., L-prolinamide derivative I catalyzed the direct enantioselective N-nitroso aldol reaction of EtCHMeCHO with PhNO to give 53% (-)-EtCMe(CH2OH)NPhOH (46% ee) after NaBH4 reduction
Chemical Communications (Cambridge, United Kingdom) published new progress about Aldehydes Role: RCT (Reactant), RACT (Reactant or Reagent). 1205-17-0 belongs to class isoquinoline, name is 2-Methyl-3-(3,4-methylenedioxyphenyl)propionaldehyde, and the molecular formula is C11H12O3, Category: isoquinoline.
Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem