Hu, Jiang-Lin published the artcileRuthenium-Catalyzed Enantioselective Addition of Carboxylic Acids to Allenes, Category: isoquinoline, the main research area is branched allylic ester enantioselective regioselective preparation; allene carboxylic acid addition ruthenium catalyst.
A ruthenium-catalyzed synthetic method for branched allylic esters I [R1 = TBSO(CH2)2, cyclopentyl, Ph(CH2)2, etc.; R2 = i-Pr, 2-thienyl, Ph, etc.] via addition of carboxylic acids to allenes was reported. Ligands were designed and prepared based on Josiphos skeleton, with which reaction achieved up to 95% yield and up to >99% enantiomeric excess. A deuterium labeling experiment was performed and a plausible mechanism was proposed. Enantiopure lactones of five- and six-membered ring were synthesized via a RCM reaction of branched allylic ester product.
ACS Catalysis published new progress about Addition reaction catalysts, stereoselective. 104-01-8 belongs to class isoquinoline, name is 4-Methoxyphenylacetic acid, and the molecular formula is C9H10O3, Category: isoquinoline.
Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem