To, Tuong A. published the artcileIron-catalyzed one-pot sequential transformations:synthesis of quinazolinones via oxidative Csp3-H bond activation using a new metal-organic framework as catalyst, SDS of cas: 104-01-8, the main research area is iron catalyst preparation; quinazolinone green preparation; phenylacetic acid aminobenzamide tandem activation cyclization iron catalyst; diamine phenylacetic acid tandem activation cyclization iron catalyst.
A new mixed-linker iron-based MOF VNU-21 [Fe3(BTC)(EDB)2·12.27H2O] was synthesized via mixed-linker synthetic strategy using 1,3,5-benzenetricarboxylic acid, 4,4′-ethynylenedibenzoic acid and FeCl2. The VNU-21 was consequently used as a recyclable heterogeneous catalyst in the one-pot synthesis of quinazolinones I [R = H, 2-Me, 4-Br, etc.; R1 = H, 7-Me, 6-F, etc.] via two steps under oxygen atm. The synthetic scheme involved iron-catalyzed oxidative Csp3-H bond activation to achieve decarboxylation of phenylacetic acids and succeeding metal-free oxidative cyclization with 2-aminobenzamides. The VNU-21 was more effective than a series of heterogeneous and homogeneous catalysts. It was possible to reutilized the iron-based framework without a considerable deterioration in catalytic performance.
Journal of Catalysis published new progress about Amides Role: RCT (Reactant), RACT (Reactant or Reagent). 104-01-8 belongs to class isoquinoline, name is 4-Methoxyphenylacetic acid, and the molecular formula is C9H10O3, SDS of cas: 104-01-8.
Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem