Lin, Hua-Chen published the artcileA Pd-H/Isothiourea Cooperative Catalysis Approach to anti-Aldol Motifs: Enantioselective α-Alkylation of Esters with Oxyallenes, Formula: C9H10O3, the main research area is oxyallene pentafluorophenyl acetate palladium benzotetramisole enantioselective diastereoselective alkylation; pentafluorophenyl oxypentenoate preparation; methyl oxy butenyl carbamate preparation; Allenes; C1-Ammonium Enolates; Enantioselectivity; Isothioureas; Palladium Catalysis.
To complement the array of substrate-based strategies, and regulate enolate geometry at the catalyst level, a direct catalytic alkylation of esters with oxyallenes was developed. Synergizing metal hydride reactivity with Lewis base catalysis resulted in a broad reaction scope with useful levels of stereocontrol (up to >99% ee). Facile derivatization of these ambiphilic linchpins was demonstrated, providing access to high-value vicinal stereocenter-containing motifs, including 1,2-amino alcs.
Angewandte Chemie, International Edition published new progress about Alkylation catalysts, stereoselective. 104-01-8 belongs to class isoquinoline, name is 4-Methoxyphenylacetic acid, and the molecular formula is C9H10O3, Formula: C9H10O3.
Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem