Indu, Satrajit et al. published their research in Organic & Biomolecular Chemistry in 2020 | CAS: 23707-37-1

Construction of key building blocks towards the synthesis of cortistatins was written by Indu, Satrajit;Telore, Rahul D.;Kaliappan, Krishna P.. And the article was included in Organic & Biomolecular Chemistry in 2020.Recommanded Product: 23707-37-1 This article mentions the following:

This work reports the construction of key building blocks towards the synthesis of cortistatins, a family of steroidal alkaloids. Cortistatin A (I), being a primary target due to its superior biol. properties over other congeners, has been prepared by two different synthetic routes. Synthesis of the precursor to the heavily substituted A-ring starting from D-glucose and construction of the DE-ring junction employing a Hajos-Parrish ketone as a chiral pool have been demonstrated. Efforts are underway to assemble these key fragments and build towards the total synthesis of cortistatin A. In the experiment, the researchers used many compounds, for example, Isoquinolin-7-amine (cas: 23707-37-1Recommanded Product: 23707-37-1).

Isoquinolin-7-amine (cas: 23707-37-1) belongs to isoquinoline derivatives. Quinoline is a catabolite of tryptophan, the basic structure of some antihypertensive drugs, such as the peripheral vasodilators prazosin and doxazosin. Lewis acid activation and nucleophilic attack can produce multiple regioisomers in quinolines and pyridines; isoquinolines generally only undergo attack at the 1-position.Recommanded Product: 23707-37-1

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem