Reactions of 6,7-dimethoxy-3,4-dihydroisoquinoline with o-quinone methides was written by Osyanin, V. A.;Ivleva, E. A.;Osipov, D. V.;Klimochkin, Yu. N.. And the article was included in Chemistry of Heterocyclic Compounds (New York, NY, United States) in 2011.Quality Control of 6,7-Dimethoxy-3,4-dihydroisoquinoline This article mentions the following:
Products of heterocyclization, 9,10-dimethoxy-12,13-dihydro-7aH,15H-naphtho[1′,2′:5,6][1,3]oxazino[2,3-a]isoquinolines, were isolated on condensation of 6,7-dimethoxy-3,4-dihydroisoquinoline with 1-[(dimethylamino)methyl]-2-naphthols. In the case of 2-hydroxybenzyl alcs., products of an aza-Michael reaction, 2-[(6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)methyl]phenols were obtained. In the experiment, the researchers used many compounds, for example, 6,7-Dimethoxy-3,4-dihydroisoquinoline (cas: 3382-18-1Quality Control of 6,7-Dimethoxy-3,4-dihydroisoquinoline).
6,7-Dimethoxy-3,4-dihydroisoquinoline (cas: 3382-18-1) belongs to isoquinoline derivatives. Quinoline is a catabolite of tryptophan, the basic structure of some antihypertensive drugs, such as the peripheral vasodilators prazosin and doxazosin. Isoquinoline-type alkaloids show biological activities similar to those of morphinane-, protoberberine-, and benzophenanthridine-type alkaloids.Quality Control of 6,7-Dimethoxy-3,4-dihydroisoquinoline
Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem