Zhang, Mingjun published the artcileGeneration and precise control of sulfonyl radicals: visible-light-activated redox-neutral formation of sulfonates and sulfonamides, Synthetic Route of 5961-59-1, the main research area is arylmethacrylamide dimethylsulfamoyl chloride iridium catalyst photochem sulfonation radical cyclization; sodium dimethyl oxoindolinyl methanesulfonate preparation; alkylsulfamoyl chloride arylmethacrylamide iridium catalyst photochem sulfonation radical cyclization; oxoindolinyl methanesulfonamide preparation.
A protocol for the generation and precise control of the sulfonyl radical from dimethylsulfamoyl chloride was reported. Different kinds of alkyl sulfonates and sulfonamides were efficiently and selectively obtained under redox-neutral conditions by controlling the reactivity of photocatalysts. A mechanism for the generation of sulfamoyl and sulfonate radicals from dimethylsulfamoyl chloride and the followed sulfonation and sulfonamidation were proposed. This reaction system offers a distinct advantage over traditional oxidation or reduction sulfonation methods in not requiring the use of sulfur dioxide, sulfonic acid, a stoichiometric reductant, or a stoichiometric oxidant. Thus, it should be of practical value for the late-stage functionalization of natural products or medicines.
Organic Chemistry Frontiers published new progress about Alkanesulfonates Role: SPN (Synthetic Preparation), PREP (Preparation). 5961-59-1 belongs to class isoquinoline, name is 4-Methoxy-N-methylaniline, and the molecular formula is C8H11NO, Synthetic Route of 5961-59-1.
Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem