Baguia, Hajar published the artcile[(DPEPhos)(bcp)Cu]PF6: a general and broadly applicable copper-based photoredox catalyst, Related Products of isoquinoline, the main research area is diphosphine copper bathocuprione complex preparation catalyst radical cyclization arylation; radical cyclization organic halide diphosphine copper bathocuprione complex catalyst; arylation heteroarene diphosphine copper bathocuprione complex catalyst.
The authors’ group recently reported the use of [(DPEPhos)(bcp)Cu]PF6 as a general Cu-based photoredox catalyst which proved efficient to promote the activation of a broad variety of organic halides, including unactivated ones. These can then participate in various radical transformations such as reduction and cyclization reactions, as well as in the direct arylation of several (hetero)arenes. These transformations provide a straightforward access to a range of small mols. of interest in synthetic chem., as well as to biol. active natural products. Altogether, [(DPEPhos)(bcp)Cu]PF6 acts as a convenient photoredox catalyst which appears to be an attractive, cheap and complementary alternative to the state-of-the-art Ir- and Ru-based photoredox catalysts. Here, the authors report a detailed protocol for the synthesis of [(DPEPhos)(bcp)Cu]PF6, as well as NMR and spectroscopic characterizations, and the authors illustrate its use in synthetic chem. for the direct arylation of (hetero)arenes and radical cyclization of organic halides. In particular, the direct arylation of N-methylpyrrole with 4-iodobenzonitrile to afford 4-(1-methyl-1H-pyrrol-2-yl)benzonitrile and the radical cyclization of N-benzoyl-N-[(2-iodoquinolin-3-yl)methyl]cyanamide to afford natural product luotonin A are detailed. The scope and limitations of this Cu-based photoredox catalyst are also briefly discussed.
Journal of Visualized Experiments published new progress about Aromatic hydrocarbons Role: RCT (Reactant), RACT (Reactant or Reagent) (heteroarenes). 151-10-0 belongs to class isoquinoline, name is 1,3-Dimethoxybenzene, and the molecular formula is C8H10O2, Related Products of isoquinoline.
Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem